Identification of novel bioactive aldehyde-modified phosphatidylethanolamines formed by lipid peroxidation
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چکیده
منابع مشابه
Proteins modified by the lipid peroxidation aldehyde 9,12-dioxo-10(E)-dodecenoic acid in MCF7 breast cancer cells.
The hydroperoxide of linoleic acid (13-HPODE) degrades to 9,12-dioxo-10(E)-dodecenoic acid (DODE), which readily modifies proteins. This study identified the major proteins in MCF7 cells modified by DODE. To reduce false positives, three methods were used to identify DODE-modified proteins. First, cells were treated with a synthetically biotinylated 13-HPODE (13-HPODE-biotin). Modified proteins...
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ژورنال
عنوان ژورنال: Free Radical Biology and Medicine
سال: 2012
ISSN: 0891-5849
DOI: 10.1016/j.freeradbiomed.2012.07.077